N-heterocyclic Compounds. 2 the stetter reaction conjugate addition of an aldehyde to an α β unsaturated compound is a superb method for the construction of 1 4 dicarbonyl compounds bearing quaternary stereocenters. While the formation of 4 5 mi was identified as a noncatalytic process the yield of 2 mp.
Herein we report chemoselective hydrogenation of 2 nitroacylbenzenes to 2 1 benzisoxazoles under ambient conditions for the first time wihch is achieved over cellulo 2020 green chemistry hot articles. Under optimal conditions 2 methyl pyrazine mp and 4 5 methyl imidazole mi were produced within 15 min with combined yields of around 40. Us20070004708a1 us10 552 493 us55249304a us2007004708a1 us 20070004708 a1 us20070004708 a1 us 20070004708a1 us 55249304 a us55249304 a us 55249304a us 2007004708 a1 us2007004708 a1 us 2007004708a1.
While the formation of 4 5 mi was identified as a noncatalytic process the yield of 2 mp.
Rovis has demonstrated that triazolium salt in the presence of a base can act as an n heterocyclic carbene organocatalyst 1 in highly enantioselective intramolecular stetter reactions. Us20070004708a1 us10 552 493 us55249304a us2007004708a1 us 20070004708 a1 us20070004708 a1 us 20070004708a1 us 55249304 a us55249304 a us 55249304a us 2007004708 a1 us2007004708 a1 us 2007004708a1. Ammoxidation of technical lignins under mild conditions is a suitable approach to artificial humic substances. N heterocyclic compounds are important chemicals and their reductive synthesis using h2 under mild conditions is attractive but challenging.
